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Endocrine Abstracts

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ea0059oc3.3 | Obesity & diabetes | SFEBES2018

Staging of non-alcoholic fatty liver disease through LC-MS/MS analysis of the urinary steroid metabolome

Moolla Ahmad , Taylor Angela , Gilligan Lorna , Boer Jasper De , Amin Amin , Pavlov David , Hughes Beverly , Hassan-Smith Zaki , Armstrong Matt , Newsome Philip , Shah Tahir , Van Gaal Luc , Verrijken An , Francque Sven , Grove Jane , Guha Neil , Aithal Guruprasad , Barnes Ellie , Arlt Wiebke , Biehl Michael , Tomlinson Jeremy

Introduction: The development of accurate non-invasive markers to diagnose and stage non-alcoholic fatty liver disease (NAFLD) is of high importance to reduce the need for an invasive liver biopsy. These markers help to stratify patients at highest risk of hepatic and cardio-metabolic complications and allow tracking of disease progression and treatment response. We have previously described alterations in glucocorticoid metabolism that are differentially regulated across the ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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